Miotine

Miotine
Names
IUPAC name
[3-[1-(Dimethylamino)ethyl]phenyl] N-methylcarbamate
Identifiers
3D model (JSmol)
ChemSpider
KEGG
UNII
  • InChI=1S/C12H18N2O2/c1-9(14(3)4)10-6-5-7-11(8-10)16-12(15)13-2/h5-9H,1-4H3,(H,13,15) ☒N
    Key: KQOUPMYYRQWZLI-UHFFFAOYSA-N ☒N
  • InChI=1/C12H18N2O2/c1-9(14(3)4)10-6-5-7-11(8-10)16-12(15)13-2/h5-9H,1-4H3,(H,13,15)
    Key: KQOUPMYYRQWZLI-UHFFFAOYAX
  • CC(C1=CC(=CC=C1)OC(=O)NC)N(C)C
Properties
C12H18N2O2
Molar mass 222.288 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.

Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.

Miotine equilibrium
Miotine equilibrium

See also



This page was last updated at 2024-03-05 15:34 UTC. Update now. View original page.

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