SNTB2

SNTB2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSNTB2, D16S2531E, EST25263, SNT2B2, SNT3, SNTL, syntrophin beta 2
External IDsOMIM: 600027 MGI: 101771 HomoloGene: 4911 GeneCards: SNTB2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_130845
NM_006750

NM_009229
NM_001368316

RefSeq (protein)

NP_006741
NP_006741.1

NP_033255
NP_001355245

Location (UCSC)Chr 16: 69.19 – 69.31 MbChr 8: 107.66 – 107.75 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Beta-2-syntrophin is a protein that in humans is encoded by the SNTB2 gene.

Function

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally related genes.

Interactions

SNTB2 has been shown to interact with ABCA1.



This page was last updated at 2024-02-01 11:23 UTC. Update now. View original page.

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